Multimodal imaging of a transcatheter aortic valve implantation within an isolated heart.

N O V E L I M A G I N G O F F U N C T I O N A L C A R D I A C A N A T O M Y is possible in isolated heart preparations when a clear perfusate is used; which, in turn, provides important insights into the device-tissue interface of implanted devices such as transcatheter valves. The implantation of a transcatheter aortic valve (TAV) (CoreValve System, Medtronic, Inc., Mounds View, Minnesota) within an isolated human heart was performed using echocardiography, fluoroscopy, and direct visualization to compare imaging modalities for better understanding of the implantation procedure (Fig. 1, Online Video 1).